IL-7   Click here for help

GtoPdb Ligand ID: 4999

Synonyms: interleukin-7
Immunopharmacology Ligand
Comment: IL-7 is produced primarily by stromal cells and exerts its effects via a receptor complex consisting of IL-7 receptor alpha (IL7R) and a common IL-2 receptor gamma subunit (IL2RG). IL-7 signaling is essential for the establishment and maintenance of normal immune system functions. IL-7 stimulates the proliferation, differentiation, trafficking and survival of a variety of T cell subsets, including naive, central memory (CM), effector memory (EM), terminally differentiated effector memory (TEMRA) and natural killer (NK) T cells.
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Synonyms Click here for help
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IL7 interleukin 7 Human prepro-interleukin-7 IL-7
Database Links Click here for help
Ensembl Gene ENSG00000104432 (Hs)
GtoPdb PubChem SID 178101696
Human Protein Atlas ENSG00000104432 (Hs)
UniProtKB P13232 (Hs)
Wikipedia Interleukin_7