dynorphin A

Ligand id: 1620

Name: dynorphin A

Species: Human, Mouse, Rat

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target
δ receptor
κ receptor
μ receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
κ receptor Rn Agonist Full agonist 10.0 – 10.3 pKi - 1-2
pKi 10.0 – 10.3 [1-2]
κ receptor Hs Agonist Full agonist 8.3 – 10.8 pKi - 3-5,7-8
pKi 8.3 – 10.8 [3-5,7-8]
μ receptor Hs Agonist Full agonist 8.1 pKi - 5
pKi 8.1 [5]
δ receptor Hs Agonist Full agonist 7.4 pKi - 5
pKi 7.4 [5]
κ receptor Mm Agonist Full agonist 9.4 pIC50 - 6
pIC50 9.4 [6]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Targets where the ligand is described in the comment field
Target Comment
Ligand mentioned in the following text fields