trimipramine   Click here for help

GtoPdb Ligand ID: 7317

Synonyms: 7162 RP | IL-6001 | Surmontil®
Approved drug
trimipramine is an approved drug (FDA (1979))
Compound class: Synthetic organic
Comment: Trimipramine is a tricyclic antidepressant (TCA) with antidepressant, anxiolytic, antipsychotic and sedative effects. Trimipramine is a racemic compound of two enantiomers; (S)-trimipramine and (R)-trimipramine. We show the non-stereo structure to represent the mixture.
Marketed formulations may contain trimipramine maleate (PubChem CID 5282318).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 6.48
Molecular weight 294.21
XLogP 4.33
No. Lipinski's rules broken 0
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Canonical SMILES CN(CC(CN1c2ccccc2CCc2c1cccc2)C)C
Isomeric SMILES CN(CC(CN1c2ccccc2CCc2c1cccc2)C)C
InChI InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1979))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
1414 trimipramine
Synonyms Click here for help
7162 RP | IL-6001 | Surmontil®
Database Links Click here for help
CAS Registry No. 739-71-9
DrugBank Ligand DB00726
DrugCentral Ligand 2758
GtoPdb PubChem SID 178103890
PubChem CID 5584
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UniChem Compound Search for chemical match using the InChIKey ZSCDBOWYZJWBIY-UHFFFAOYSA-N
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Wikipedia Trimipramine