sulfadiazine   Click here for help

GtoPdb Ligand ID: 12635

Approved drug
sulfadiazine is an approved drug (FDA (1941), UK (2008))
Compound class: Synthetic organic
Comment: Sulfadiazine is a sulfonamide with broad-spectrum antimicrobial activity [4]. It is used in the treatment of toxoplasmosis, an infection with the protozoan parasite Toxoplasma gondi that can cause serious complications during pregnancy and in patients with weakened immune systems. Dermatological formulations containing silver sulfadiazine (PubChem CID 441244) are used to prevent and treat wound infections.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 105.29
Molecular weight 250.28
XLogP -1.47
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
Isomeric SMILES C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
InChI InChI=1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)
InChI Key SEEPANYCNGTZFQ-UHFFFAOYSA-N