M5717

Ligand id: 9737

Name: M5717

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 57.7
Molecular weight 462.24
XLogP 3.43
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. BaragaƱa B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G et al.. (2015)
A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature, 522 (7556): 315-20. [PMID:26085270]
2. Gilbert IH, Norcross N, Baragana Ruibal B, Porzelle A. (2013)
Anti-malarial agents.
Patent number: WO2013153357A1. Assignee: University Of Dundee. Priority date: 10/04/2012. Publication date: 17/10/2013.