Ligand id: 9676

Name: proguanil

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 88.79
Molecular weight 253.11
XLogP 1.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Boggild AK, Parise ME, Lewis LS, Kain KC. (2007)
Atovaquone-proguanil: report from the CDC expert meeting on malaria chemoprophylaxis (II).
Am. J. Trop. Med. Hyg., 76 (2): 208-23. [PMID:17297027]
2. Srivastava IK, Vaidya AB. (1999)
A mechanism for the synergistic antimalarial action of atovaquone and proguanil.
Antimicrob. Agents Chemother., 43 (6): 1334-9. [PMID:10348748]