IL-11

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Ligands
IL-11 (Human)

GtoPdb Ligand ID: 4976

Synonyms: interleukin-11

Compound class: Endogenous peptide in human, mouse or rat

Comment: IL-11 is a member of the IL-6-type cytokine family. The recombinant form of human IL-11 is an approved drug with INN oprelvekin.

Species: Human

Summary
Biological activity
References
Structure
Similar ligands
Immunopharmacology

Immunopharmacology Comments
IL-11 is a thrombopoietic growth factor important for megakaryocyte maturation (i.e. platelet production). Its platelet producing activity is used clinically to treat/prevent severe thrombocytopenia.

Immunopharmacology Comments

IL-11 is a thrombopoietic growth factor important for megakaryocyte maturation (i.e. platelet production). Its platelet producing activity is used clinically to treat/prevent severe thrombocytopenia.