IL-1 receptor antagonist   Click here for help

GtoPdb Ligand ID: 5878

Synonyms: IL-1ra | interleukin-1 receptor antagonist protein | IRAP
Immunopharmacology Ligand
Comment: A recombinant, non-glycosylated version of this protein is marketed as rheumatoid arthritis drug anakinra.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-1 receptor, type I
Interleukin-2 receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-1 receptor, type I Ligand is endogenous in the given species Hs Antagonist Antagonist - - -
Interleukin-2 receptor Ligand is endogenous in the given species Hs Antagonist Antagonist - - -
Targets where the ligand is described in the comment field
Target Comment