LH   Click here for help

GtoPdb Ligand ID: 1159

Synonyms: luteinising hormone | luteinizing hormone
Approved drug
LH is an approved drug (FDA (2004))
Compound class: Endogenous peptide in human, mouse or rat
Comment: The approved drug lutropin alfa (INN) is the recombinant form of human LH and is composed of two subunits (α = 92 amino acids, β = 121 amino acids).
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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Subunits
LH β subunit
glycoprotein hormone common alpha subunit
Peptide Sequence Click here for help
No information available.
Post-translational Modification
The production of biologically active LH requires appropriately folded and glycosylated LHβ and common α subunits that assemble to form the active LH heterodimer [1].