- Guide to PHARMACOLOGY
Synonyms: UK432,097 | UK432097
Compound class: Synthetic organic
Comment: Selective agonist of the adenosine A2A receptor
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Guo D, Mulder-Krieger T, IJzerman AP, Heitman LH. (2012)
Functional efficacy of adenosine A₂A receptor agonists is positively correlated to their receptor residence time.
Br J Pharmacol, 166 (6): 1846-59. [PMID:22324512]
2. Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. (2011)
Structure of an agonist-bound human A2A adenosine receptor.
Science, 332 (6027): 322-7. [PMID:21393508]