1400W

Ligand id: 5102

Name: 1400W

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 64.4
Molecular weight 177.13
XLogP 0.2
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Laszlo F, Whittle BJ, Knowles RG. (1997)
1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo.
J. Biol. Chem., 272 (8): 4959-63. [PMID:9030556]