IL-4   Click here for help

GtoPdb Ligand ID: 4996

Synonyms: B-cell stimulatory factor 1 | binetrakin | interleukin-4 | pitrakinra
Immunopharmacology Ligand
Comment: IL-4 shares sequence and structural homology with IL-13.
Species: Human
1. Hart TK, Blackburn MN, Brigham-Burke M, Dede K, Al-Mahdi N, Zia-Amirhosseini P, Cook RM. (2002)
Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma.
Clin Exp Immunol, 130 (1): 93-100. [PMID:12296858]
2. Sokol CL, Barton GM, Farr AG, Medzhitov R. (2008)
A mechanism for the initiation of allergen-induced T helper type 2 responses.
Nat Immunol, 9 (3): 310-8. [PMID:18300366]