IL-4   Click here for help

GtoPdb Ligand ID: 4996

Synonyms: B-cell stimulatory factor 1 | binetrakin | interleukin-4 | pitrakinra
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: IL-4 shares sequence and structural homology with IL-13.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-4 receptor type I
Interleukin-4 receptor type II
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-4 receptor type I Ligand is endogenous in the given species Hs Agonist Agonist - - -
⤷
Interleukin-4 receptor type II Ligand is endogenous in the given species Hs Agonist Agonist - - -
⤷
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
pascolizumab Peptide Primary target of this compound Hs Antibody Binding 8.0 pIC50 - 1
⤷ pIC50 8.0 (IC50 1x10-8 M) [1]