- Guide to PHARMACOLOGY
Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Jakubík J, Bacáková L, el-Fakahany EE, Tucek S. (1995)
Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.
J Pharmacol Exp Ther, 274 (3): 1077-83. [PMID:7562472]
2. Peralta EG, Ashkenazi A, Winslow JW, Ramachandran J, Capon DJ. (1988)
Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes.
Nature, 334 (6181): 434-7. [PMID:2841607]
3. Peralta EG, Ashkenazi A, Winslow JW, Smith DH, Ramachandran J, Capon DJ. (1987)
Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.
EMBO J, 6 (13): 3923-9. [PMID:3443095]