[3H]QNB   Click here for help

GtoPdb Ligand ID: 318

Synonyms: [3H]quinuclidinylbenzilate
 Ligand is labelled  Ligand is radioactive
Compound class: Synthetic organic
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 49.77
Molecular weight 337.17
XLogP 3.16
No. Lipinski's rules broken 0
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Canonical SMILES O=C(C(c1ccccc1)(c1ccccc1)O)OC1CN2CCC1CC2
Isomeric SMILES O=C(C(c1ccccc1)(c1ccccc1)O)OC1CN2CCC1CC2
InChI InChI=1S/C21H23NO3/c23-20(25-19-15-22-13-11-16(19)12-14-22)21(24,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,16,19,24H,11-15H2
1. Jakubík J, Bacáková L, el-Fakahany EE, Tucek S. (1995)
Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.
J Pharmacol Exp Ther, 274 (3): 1077-83. [PMID:7562472]
2. Peralta EG, Ashkenazi A, Winslow JW, Ramachandran J, Capon DJ. (1988)
Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes.
Nature, 334 (6181): 434-7. [PMID:2841607]
3. Peralta EG, Ashkenazi A, Winslow JW, Smith DH, Ramachandran J, Capon DJ. (1987)
Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.
EMBO J, 6 (13): 3923-9. [PMID:3443095]