1-phenylbiguanide   Click here for help

GtoPdb Ligand ID: 2284

Compound class: Synthetic organic
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 102.78
Molecular weight 177.1
XLogP -0.31
No. Lipinski's rules broken 0
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Canonical SMILES NC(=Nc1ccccc1)N=C(N)N
Isomeric SMILES NC(=Nc1ccccc1)N=C(N)N
InChI InChI=1S/C8H11N5/c9-7(10)13-8(11)12-6-4-2-1-3-5-6/h1-5H,(H6,9,10,11,12,13)
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Cloning and functional expression of a human 5-hydroxytryptamine type 3AS receptor subunit.
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Allosteric interactions among agonists and antagonists at 5-hydroxytryptamine3 receptors.
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Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors.
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Pharmacological characterization of the apparent splice variants of the murine 5-HT3 R-A subunit expressed in Xenopus laevis oocytes.
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Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells.
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Molecular cloning, functional expression, and pharmacological characterization of 5-hydroxytryptamine3 receptor cDNA and its splice variants from guinea pig.
Mol Pharmacol, 53 (2): 202-12. [PMID:9463477]
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Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species.
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