Ligand id: 10410

Name: MK-4815

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 3
Topological polar surface area 46.25
Molecular weight 235.19
XLogP 4.8
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Anthony MP, Burrows JN, Duparc S, Moehrle JJ, Wells TN. (2012)
The global pipeline of new medicines for the control and elimination of malaria.
Malar. J., 11: 316. [PMID:22958514]
2. Powles MA, Allocco J, Yeung L, Nare B, Liberator P, Schmatz D. (2012)
MK-4815, a potential new oral agent for treatment of malaria.
Antimicrob. Agents Chemother., 56 (5): 2414-9. [PMID:22314528]