Synonyms: MK4815
Compound class:
Synthetic organic
Comment: MK-4815 is a small molecule with promising antimalarial activity [2].
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
|
Guide to Malaria Pharmacology Comments |
MK-4815 was identified by a phenotypic whole cell high-throughput screen of the Merck proprietary compound collection and considered to have potential as a therapy for acute P. falciparum malaria [2], although it has not progressed beyond preclinical testing due to a narrow safety window [1]. Potential Target/Mechanism Of Action: As the precise MOA of MK-4815 is not yet known, we do not have a molecular target for this compound. |