- Guide to PHARMACOLOGY
Compound class: Synthetic organic
Comment: MK-4815 is a small molecule with promising antimalarial activity .
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|Guide to Malaria Pharmacology Comments|
|MK-4815 was identified by a phenotypic whole cell high-throughput screen of the Merck proprietary compound collection and considered to have potential as a therapy for acute P. falciparum malaria , although it has not progressed beyond preclinical testing due to a narrow safety window .
Potential Target/Mechanism Of Action: As the precise MOA of MK-4815 is not yet known, we do not have a molecular target for this compound.