amodiaquine

Ligand id: 10018

Name: amodiaquine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 48.39
Molecular weight 355.15
XLogP 4.15
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
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4. Zeldin DC, DuBois RN, Falck JR, Capdevila JH. (1995)
Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform.
Arch. Biochem. Biophys., 322 (1): 76-86. [PMID:7574697]
5. (2015)
Treatment of uncomplicated Plasmodium falciparum malaria.  In  Guidelines for the Treatment of Malaria. Third edition. (World Health Organization) . [PMID:26020088] [ISBN:9789241549127]