bortezomib

Ligand id: 6391

Name: bortezomib

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 11
Topological polar surface area 124.44
Molecular weight 384.2
XLogP 1.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Guide to Malaria Pharmacology Comments
Bortezomib blocks intraerythrocytic development prior to DNA synthesis, but had no effect on parasite egress or invasion [8].