- Guide to PHARMACOLOGY
Synonyms: Kelfizine® | sulfamethopyrazine | sulfamethoxypyrazine | sulfametopyrazine
Compound class: Synthetic organic
Comment: Sulfalene is a sulfonamide containing compound with antimalarial activity.
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|Guide to Malaria Pharmacology Comments|
|Sulfalene is a sulfonamide containing compound, a chemical class that includes the approved antimalarial drug sulfadoxine. Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes (including Plasmodium sp.) and plants [1-2].|