- Guide to PHARMACOLOGY
Molecular properties generated using the CDK
|Guide to Malaria Pharmacology Comments|
|The use of halofuginone as an antimalarial medicine is precluded by intolerable side-effects and it is used instead as an antiprotozoal agent in veterinary medicine.
Potential Target/Mechanism Of Action: halofuginone activates the amino acid response pathway by direct inhibition of the PfPRS activity of glutamyl-prolyl tRNA synthetase (EPRS) .