halofuginone [Ligand Id: 10153] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1197091 (Halofuginone, Ht-100, HT-100)
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7]
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum Dd2 [GtoPdb: 3056]
  • This target only has 0 pki data point
  • 0
1 CHEMBL1197091_lig_chart_1 Plasmodium falciparum proline--tRNA ligase Plasmodium falciparum 3D7Plasmodium falciparum Dd2
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7]
GtoPdb Parasite growth inhibition assay - 9.07 pEC50 0.86 nM EC50 Sci Transl Med (2015) 7: 288ra77 [PMID:25995223]
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum Dd2 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 9.09 pEC50 0.81 nM EC50 Sci Transl Med (2015) 7: 288ra77 [PMID:25995223]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]