halofuginone [Ligand Id: 10153] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1197091 (Halofuginone, Ht-100, HT-100) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium berghei [GtoPdb: 3056] | ||||||||
| GtoPdb | Parasite liver stage assay | - | 7.77 | pIC50 | 17 | nM | IC50 | ChemMedChem (2012) 7: 844-9 [PMID:22438279] |
| Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 9.07 | pEC50 | 0.86 | nM | EC50 | Sci Transl Med (2015) 7: 288ra77 [PMID:25995223] |
| Plasmodium falciparum prolyl-tRNA synthetase in Plasmodium falciparum Dd2 [GtoPdb: 3056] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 9.09 | pEC50 | 0.81 | nM | EC50 | Sci Transl Med (2015) 7: 288ra77 [PMID:25995223] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]
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