- Guide to PHARMACOLOGY
Synonyms: CpG 7909 | CpG7909 | PF 3512676 | PF-3512676 | ProMune | VaxImmune
Compound class: Synthetic organic
Comment: Agatolimod is synthetic CpG oligodeoxynucleotide that acts as a TLR9 agonist . We show the parent molecule, whereas the USAN specifies agatolimod sodium (PubChem CID 56841789), and the synonyms we list may also refer to the sodium congener. Its nucleotide sequence is d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T).
|Binding of agatolimod to TLR9 triggers innate and adaptive immune responses that have the potential to promote an effective antitumour immune response , and/or enhance the efficacy of other anti-cancer chemotherapeutics.It has also been tested for prevention and treatment of infectious diseases, allergies, and asthma .|