- Guide to PHARMACOLOGY
Synonyms: CpG 7909 | CpG7909 | PF 3512676 | PF-3512676 | ProMune | VaxImmune
Compound class: Synthetic organic
Comment: Agatolimod is synthetic CpG oligodeoxynucleotide that acts as a TLR9 agonist . We show the parent molecule, whereas the USAN specifies agatolimod sodium (PubChem CID 56841789), and the synonyms we list may also refer to the sodium congener. Its nucleotide sequence is d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T).
|No information available.|
|Summary of Clinical Use|
|Agatolimod was investigated as an immuno-oncology therapeutic [2-3] and although manyPhase 2 clinical trials have been completed, development seems to have ceased. All trials in lung cancer were terminated by the developer in 2007, due to lack of significant efficacy in interim anaylses.|