- Guide to PHARMACOLOGY
Synonyms: interleukin-3 (IL-3) | multilineage-colony-stimulating factor (mCSF)
Compound class: Endogenous peptide in human, mouse or rat
Comment: IL-3 and GM-CSF share certain functional similarities.
|IL-3 is secreted by basophils and activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. Additionally, IL-3 acts in concert with other cytokines to stimulate proliferation of all cells in the myeloid lineage (granulocytes, monocytes, and dendritic cells).|