IL-24   Click here for help

GtoPdb Ligand ID: 4990

Synonyms: interleukin-24 | MDA-7 | melanoma differentiation-associated gene 7 protein
Immunopharmacology Ligand
Comment: IL-24 is an IL-10 related type II cytokine.
Species: Human
Immunopharmacology Comments
IL-24 is produced by monocytes, Th2 cells and melanocytes [1]. It stimulates the JAK/STAT signalling pathway via interaction with the IL-20 or IL-22 receptors. It is involved in inflammation and epidermal cell function and has proapoptotic activity.