Immunopharmacology Comments

IL-21 is expressed by activated human CD4+ T cells, is upregulated in Th2 [5] and Th17 T helper cells [4] and T follicular cells. IL-21 regulates NK T cells in an autocrine manner.

Immunopharmacology Disease
Disease	X-Refs	Comment	References
Lymphoma, non-hodgkin, familial	Disease Ontology: DOID:0060060 OMIM: 605027	HL cancer cells produce IL-21 which could explain the clustering of other immune cells around HL cells observed in vitro.	3