fenoprofen   Click here for help

GtoPdb Ligand ID: 4820

Synonyms: fenoprofen calcium | Nalfon®
Approved drug Immunopharmacology Ligand
fenoprofen is an approved drug (FDA (1976))
Compound class: Synthetic organic
Comment: Fenoprofen isa nonsteroidal anti-inflammatory drug, which is pharmacologically similar to aspirin, with similar anti-inflammatory analgesic and antipyretic actions.
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View more information in the IUPHAR Pharmacology Education Project: fenoprofen

2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 46.53
Molecular weight 242.09
XLogP 3.14
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES OC(=O)C(c1cccc(c1)Oc1ccccc1)C
Isomeric SMILES OC(=O)C(c1cccc(c1)Oc1ccccc1)C
InChI InChI=1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17)
InChI Key RDJGLLICXDHJDY-UHFFFAOYSA-N
No information available.
Summary of Clinical Use Click here for help
Fenoprofen is used to treat inflammatory conditions such as rheumatoid- and osteo-arthritis in addition to being used for pain relief.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Fenoprofen may reduce inflammation by acting to reduce cyclooxegenase activity and synthesis of pro-inflammatory prostaglandin.