- Guide to PHARMACOLOGY
Synonyms: MMV1582617 | NVP-INE963
Compound class: Synthetic organic
Comment: INE963 is a potent antimalarial compound identified by the Novartis Institute for Tropical Diseases (NITD) during an optimization study of a series of 5-aryl-2-amino-imidazothiadiazole (ITD) derivatives . The compound has progressed to clinical evaluation and was awarded MMV Project of the Year (2019).
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
|No information available.|
|Summary of Clinical Use|
|Recruitment has commenced for a Phase 1 clinical study of INE963 (safety, tolerability and pharmacokinetics in healthy volunteers).|
|Clinical Trial ID||Title||Type||Source||Comment||References|
|NCT04896632||Study of Safety, Tolerability, and Pharmacokinetics of INE963 in Healthy Participants||Phase 1 Interventional||Novartis|