itolizumab   Click here for help

GtoPdb Ligand ID: 9421

Synonyms: Alzumab® | T1h
Approved drug Immunopharmacology Ligand
itolizumab is an approved drug (DCGI (India; 2013))
Compound class: Antibody
Comment: Itolizumab is a first in class humanized IgG1 monoclonal antibody targeting T cell CD6. It is being developed by Biocon Limited for its anti-inflammatory potential in autoimmune conditions.
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Selectivity at other protein targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD6 Primary target of this compound Hs Antibody Binding 7.2 pKi - 1
pKi 7.2 (Ki 6x10-8 M) [1]