CXCL16   Click here for help

GtoPdb Ligand ID: 855

Immunopharmacology Ligand
Comment: CXC chemokine ligand (CXCL) 16 is a ligand for chemokine receptor CXCR6. Once cleaved from the cell membrane CXCL16 acts as a chemoattractant for activated CD8 T cells, NKT cells and Th1-polarized T cells that express CXCR6.
Species: Human
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Natural/Endogenous Targets
Target
CXCR6
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CXCR6 Ligand is endogenous in the given species Hs Agonist Full agonist 9.0 pKd - 2
pKd 9.0 (Kd 1x10-9 M) [2]