IL-27   Click here for help

GtoPdb Ligand ID: 6151

Immunopharmacology Ligand
Comment: IL-27 is an IL-12 family cytokine. It is a heterodimeric cytokine that contains an α and a β subunit and is expressed by activated antigen presenting cells [1]. IL-27 interaction with its receptor complex activates the JAK/STAT and p38 MAPK pathways.
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
EBI3 Epstein-Barr virus induced 3 Human prepro-interleukin-27 subunit β IL27 subunit, IL35 subunit
IL27 interleukin 27 Human prepro-interleukin 27 IL-27, IL-27A, IL27A, IL27p28, IL30, interleukin 30, MGC71873, p28
Database Links Click here for help
Ensembl Gene ENSG00000105246 (Hs), ENSG00000197272 (Hs)
GtoPdb PubChem SID 178102772
Human Protein Atlas ENSG00000105246 (Hs), ENSG00000197272 (Hs)
Immunopaedia Search IL-27
Wikipedia IL-27