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IL-21   Click here for help

GtoPdb Ligand ID: 4987

Synonyms: interleukin-21 | ZA11
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: IL-21 acts via the IL-21 receptor expressed on the surface of T, B and NK cells.
Species: Human
Peptide Sequence Click here for help
QGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPS
TNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
Selected 3D Structures
PDB Id: 2OQP
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
Predicted N-linked glycosylation of asparagine residue at position 68; disulphide bond formation between cysteine residues at positions 42 and 93, and 49 and 96