Quaternary Structure: Complexes

Interleukin-12 receptor

Interleukin-23 receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	662	19p13.11	IL12RB1	interleukin 12 receptor subunit beta 1
Mouse	1	738	8 34.21 cM	Il12rb1	interleukin 12 receptor, beta 1
Rat	-	-		Il12rb1	interleukin 12 receptor subunit beta 1

Previous and Unofficial Names

CD212 | interleukin 12 receptor, beta 1 | interleukin 12 receptor

Database Links
Alphafold	P42701 (Hs), Q60837 (Mm)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL4523226 (Hs)
Ensembl Gene	ENSG00000096996 (Hs), ENSMUSG00000000791 (Mm), ENSRNOG00000019216 (Rn)
Entrez Gene	3594 (Hs), 16161 (Mm)
Human Protein Atlas	ENSG00000096996 (Hs)
KEGG Gene	hsa:3594 (Hs), mmu:16161 (Mm)
OMIM	601604 (Hs)
Pharos	P42701 (Hs)
UniProtKB	P42701 (Hs), Q60837 (Mm)
Wikipedia	IL12RB1 (Hs)

Immunopharmacology Comments

This protein is a subunit of both the IL-12 and IL-23 cytokine receptors.

Immuno Process Associations

Immuno Process:  Inflammation

Immuno Process:  T cell (activation)

Immuno Process:  B cell (activation)

Immuno Process:  Immune regulation

Immuno Process:  Immune system development

Immuno Process:  Cytokine production & signalling

Immuno Process:  Chemotaxis & migration

Immuno Process:  Cellular signalling