Synonyms: Ro-1079070/194 | RS-079070-194 | Valcyte®
valganciclovir is an approved drug (FDA (2002, prior history not available))
Compound class:
Synthetic organic
Comment: Valcyte® contains valganciclovir hydrochloride (PubChem CID 110632). This is a prodrug of ganciclovir (PubChem CID 3454). The INN document for this drug specifies that there is a chiral centre at (position t8) and the INN-assigned compound consists of two epimers depending on the stereochemistry at this position. The structure shown here does not specify stereochemistry at this point and represents the mixture. This is represented by the '?' in the InChI standard identifier on the 'Structure' tab.
![]() View more information in the IUPHAR Pharmacology Education Project: valganciclovir |
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (2002, prior history not available)) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
IUPAC Name ![]() |
2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoate |
International Nonproprietary Names ![]() |
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INN number | INN |
7650 | valganciclovir |
Synonyms ![]() |
Ro-1079070/194 | RS-079070-194 | Valcyte® |
Database Links ![]() |
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CAS Registry No. | 175865-60-8 (source: Scifinder) |
ChEMBL Ligand | CHEMBL1201314 |
DrugBank Ligand | DB01610 |
DrugCentral Ligand | 2801 |
GtoPdb PubChem SID | 178101427 |
PubChem CID | 135413535 |
Search Google for chemical match using the InChIKey | WPVFJKSGQUFQAP-GKAPJAKFSA-N |
Search Google for chemicals with the same backbone | WPVFJKSGQUFQAP |
Search PubMed clinical trials | valganciclovir |
Search PubMed titles | valganciclovir |
Search PubMed titles/abstracts | valganciclovir |
UniChem Compound Search for chemical match using the InChIKey | WPVFJKSGQUFQAP-GKAPJAKFSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | WPVFJKSGQUFQAP-GKAPJAKFSA-N |
Wikipedia | Valganciclovir |