AMG3054   

GtoPdb Ligand ID: 9587

Comment: Apelin mimetic peptide agonist with reduced conformational flexibility, adopts a lactam constrained curved structure [1].
Peptide Sequence
KFRRQRPXXQHKKXXPX
Lys-Phe-Arg-Arg-Gln-Arg-Pro-hArg-Cha-Glu-His-Lys-Lys-Oic-Nle-Pro-4-Cl-Phe
Chemical Modification
hArg, Cha, Oic, Nle and 4-Cl-Phe are unnatural amino acid counterparts. There is a lactam ring between Glu8 and Lys13 [1].