dosulepin   Click here for help

GtoPdb Ligand ID: 7549

Synonyms: Dothep® | dothiepin | Prothiaden®
Approved drug
dosulepin is an approved drug
Compound class: Synthetic organic
Comment: Dosulepin is a tricyclic antidepressant. Functionally it acts as a serotonin-norepinephrine reuptake inhibitor (SNRI) with anticholinergic, antihistamine, and antiadrenergic effects.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 28.54
Molecular weight 295.14
XLogP 4.56
No. Lipinski's rules broken 0
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Canonical SMILES CN(CCC=C1c2ccccc2SCc2c1cccc2)C
Isomeric SMILES CN(CC/C=C/1\c2ccccc2SCc2c1cccc2)C
InChI InChI=1S/C19H21NS/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/b17-11-
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Molecular structure representations generated using Open Babel