relaxin-1   Click here for help

GtoPdb Ligand ID: 1988

Synonyms: H1 relaxin
Compound class: Endogenous peptide in human, mouse or rat
Comment: A heterodimer containing disulfide-linked A and B subunits that are each cleaved from the relaxin 1 gene (RLN1) product.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

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View more information in the IUPHAR Pharmacology Education Project: relaxin

Subunits
relaxin-1 (A chain)
relaxin-1 (B chain)
Peptide Sequence Click here for help
No information available.
Post-translational Modification
Fully active H1 relaxin is a heterodimer of the B chain and the A chain linked by two disulfide bonds, the first between B chain (residue 35) and A chain (residue 172), and the second between B chain (residue 47) and A chain (residue 185).