Synonyms: Acelex® (S. Korea) | CG-100649 | CG100649
polmacoxib is an approved drug
Compound class:
Synthetic organic
Comment: Polmacoxib is a first-in-class dual COX2/carbonic anhydrase I/II inhibitor, a potential non-steroidal anti-inflammatory drug (NSAID) with postulated attenuated cardiovascular risk compared to selective COX2 inhibiting NSAIDs [1].
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References |
1. Skarke C, Alamuddin N, Lawson JA, Cen L, Propert KJ, Fitzgerald GA. (2012)
Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. Clin Pharmacol Ther, 91 (6): 986-93. [PMID:22278334] |