- Guide to PHARMACOLOGY
Synonyms: PF 04691502 | PF04691502
Compound class: Synthetic organic
Comment: PF-04691502 is an ATP-competitive dual PI3K/mTOR inhibitor. The discovery and structure of PF-04691502 is reported in . PubChem CID 25033539 shows the chemical structure without stereochemistry.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Liu KK, Zhu J, Smith GL, Yin MJ, Bailey S, Chen JH, Hu Q, Huang Q, Li C, Li QJ et al.. (2011)
Highly Selective and Potent Thiophenes as PI3K Inhibitors with Oral Antitumor Activity.
ACS Med Chem Lett, 2 (11): 809-13. [PMID:24900269]