Synonyms: ANG-2
Compound class:
Endogenous peptide in human, mouse or rat
Species: Human
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References |
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Bispecific, bivalent anti-VEGF/anti-ANG-2 antibodies. Patent number: US8945552 B2. Assignee: Hoffmann-La Roche Inc.. Priority date: 26/03/2010. Publication date: 03/02/2015. |
2. Daly C, Eichten A, Castanaro C, Pasnikowski E, Adler A, Lalani AS, Papadopoulos N, Kyle AH, Minchinton AI, Yancopoulos GD et al.. (2013)
Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition. Cancer Res, 73 (1): 108-18. [PMID:23149917] |
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Ang2 antibodies. Patent number: WO2015179166A1. Assignee: Eli Lilly And Company. Priority date: 19/05/2014. Publication date: 26/11/2015. |
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Specific binding agents of human angiopoietin-2. Patent number: US7138370 B2. Assignee: Amgen Inc.. Priority date: 11/10/2001. Publication date: 21/11/2006. |
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Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases. EMBO Mol Med, 8 (11): 1265-1288. [PMID:27742718] |