[11C]GlySar   Click here for help

GtoPdb Ligand ID: 4489

Synonyms: [11C]-GlySar | [11C]glycylsarcosine
 Ligand is labelled  Ligand is radioactive
Compound class: Synthetic organic
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 83.63
Molecular weight 146.07
XLogP -4.04
No. Lipinski's rules broken 0
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Canonical SMILES CN(C(=O)CN)CC(=O)O
Isomeric SMILES [11CH3]N(C(=O)CN)CC(=O)O
InChI InChI=1S/C5H10N2O3/c1-7(3-5(9)10)4(8)2-6/h2-3,6H2,1H3,(H,9,10)/i1-1
1. Mitsuoka K, Miyoshi S, Kato Y, Murakami Y, Utsumi R, Kubo Y, Noda A, Nakamura Y, Nishimura S, Tsuji A. (2008)
Cancer detection using a PET tracer, 11C-glycylsarcosine, targeted to H+/peptide transporter.
J Nucl Med, 49 (4): 615-22. [PMID:18344442]
2. Nabulsi NB, Smith DE, Kilbourn MR. (2005)
[11C]Glycylsarcosine: synthesis and in vivo evaluation as a PET tracer of PepT2 transporter function in kidney of PepT2 null and wild-type mice.
Bioorg Med Chem, 13 (8): 2993-3001. [PMID:15781409]