- Guide to PHARMACOLOGY
Compound class: Synthetic organic
Comment: Compound 46 is a non-peptidic antagonist of the neuropeptide FF1 receptor . It has low binding affinity for opioid receptors.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Journigan VB, Mésangeau C, Vyas N, Eans SO, Cutler SJ, McLaughlin JP, Mollereau C, McCurdy CR. (2014)
Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors.
J Med Chem, 57 (21): 8903-27. [PMID:25268943]