Synonyms: compound 17j [PMID: 2148514] | TP-434 | TP434 | Xerava®
eravacycline is an approved drug (EMA & FDA (2018))
Compound class:
Synthetic organic
Comment: Eravacycline is a parenteral tetracycline antibacterial.
|
|
References |
1. Solomkin J, Evans D, Slepavicius A, Lee P, Marsh A, Tsai L, Sutcliffe JA, Horn P. (2017)
Assessing the Efficacy and Safety of Eravacycline vs Ertapenem in Complicated Intra-abdominal Infections in the Investigating Gram-Negative Infections Treated With Eravacycline (IGNITE 1) Trial: A Randomized Clinical Trial. JAMA Surg, 152 (3): 224-232. [PMID:27851857] |
2. Solomkin JS, Gardovskis J, Lawrence K, Montravers P, Sway A, Evans D, Tsai L. (2019)
IGNITE4: Results of a Phase 3, Randomized, Multicenter, Prospective Trial of Eravacycline vs Meropenem in the Treatment of Complicated Intraabdominal Infections. Clin Infect Dis, 69 (6): 921-929. [PMID:30561562] |
3. Solomkin JS, Sway A, Lawrence K, Olesky M, Izmailyan S, Tsai L. (2019)
Eravacycline: a new treatment option for complicated intra-abdominal infections in the age of multidrug resistance. Future Microbiol, 14: 1293-1308. [PMID:31570004] |
4. Xiao XY, Hunt DK, Zhou J, Clark RB, Dunwoody N, Fyfe C, Grossman TH, O'Brien WJ, Plamondon L, Rönn M et al.. (2012)
Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. J Med Chem, 55 (2): 597-605. [PMID:22148514] |