Synonyms: Gefitinib-based PROTAC 3 [1]
Compound class:
Synthetic organic
Comment: This compound is a gefitinib-based VHL-recruiting EGFR degrader (PROTAC; proteolysis targeting chimera) [1].
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References |
1. Burslem GM, Smith BE, Lai AC, Jaime-Figueroa S, McQuaid DC, Bondeson DP, Toure M, Dong H, Qian Y, Wang J et al.. (2018)
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. Cell Chem Biol, 25 (1): 67-77.e3. [PMID:29129716] |