- Guide to PHARMACOLOGY
Compound class: Synthetic organic
Comment: E209 is a fully synthetic tetraoxane analogue with potent antimalarial activity .
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
1. O'Neill PM, Amewu RK, Charman SA, Sabbani S, Gnädig NF, Straimer J, Fidock DA, Shore ER, Roberts NL, Wong MH et al.. (2017)
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nat Commun, 8: 15159. [PMID:28537265]