Compound class:
Synthetic organic
Comment: Compound 24 is the lead identified in a medicinal chemistry study of the 6-Chloro-2-arylvinylquinolines, a novel class of small molecules with promising antimalarial activity [1].
The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. |
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Guide to Malaria Pharmacology Comments |
Compound 24 is a fast-acting antimalarial that targets the trophozoites (asexual blood stage) and also demontrates transmission blocking potential [1]. Potential Target/Mechanism Of Action: As the precise mechanism of action of compound 24 is not yet known, we do not have a molecular target for this compound. |