- Guide to PHARMACOLOGY
Synonyms: CGS 27023A | CGS27023A | MMI270
Compound class: Synthetic organic
Comment: CGS-27023A is reported as a potent pan-inhibitor of matrix metalloproteinases .
Note that CGS-27023A imay be used experimentally as the hydrochloride salt (PubChem CID 9888897).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|No information available.|
|Summary of Clinical Use|
|This compound (with alternative reseach code MMI270) was assessed for antineoplastic activity in Phase 1 clinical trial in patients with advanced solid cancer .|