- Guide to PHARMACOLOGY
Synonyms: AHR-10282B | Bromday® | Prolensa® | Xibrom®
bromfenac is an approved drug (FDA (2004), EMA (2011))
Compound class: Synthetic organic
Comment: Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID).
Marketed formulations may contain bromfenac sodium (PubChem CID 23693301).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: bromfenac
|No information available.|
|Summary of Clinical Use|
|Used to minimise clouding of the lens caused by post-operative inflammation following cataract removal.|
|Mechanism Of Action and Pharmacodynamic Effects|
|As with other NSAIDs, this drug reduces prostaglandin synthesis by reducing cyclooxegenase (COX) activity.|
For extended ADME data see the following:
European Medicines Agency (EMA)