- Guide to PHARMACOLOGY
Synonyms: Acular® | Toradol®
ketorolac is an approved drug (FDA (1989))
Compound class: Synthetic organic
Comment: Ketorolac is a heterocyclic acetic acid class non-steroidal anti-inflammatory drug (NSAID). It acts as a non-selective COX inhibitor. The administered drug is a racemic mixture of enantiomers. We show the chemical structure without specified stereochemistry to represent the mixture.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: ketorolac
|No information available.
|Summary of Clinical Use
|Approved for short-term management of moderately severe acute pain and prophylaxis and reduction of inflammation and associated symptoms following ocular surgery.
|Mechanism Of Action and Pharmacodynamic Effects
|For an overview of the mechanism of action of ketorolac, please use the link to the DrugBank page for this ligand which is on the 'Summary' tab.